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If you think you’ve taken too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away.
Methadone should be given with caution and the initial dose reduced hinein certain patients, such as the elderly and debilitated and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy, or urethral stricture.
The endpoint of titration is achievement of adequate pain relief, balanced against tolerability of opioid side effects. If a patient develops intolerable opioid related side effects, the methadone dose, or dosing interval, may need to Beryllium adjusted.
Optimal methadone initiation and dose titration strategies for the treatment of pain have not been determined. Published equianalgesic conversion ratios between methadone and other opioids are imprecise, providing at best, only Fortpflanzungsgemeinschaft averages that cannot Beryllium applied consistently to all patients. It should Beryllium noted that many commonly cited equianalgesia tables only present relative analgesic potencies of single opioid doses in non-tolerant patients, thus greatly underestimating methadone's analgesic potency, and its potential for adverse effects in repeated-dose settings.
Particular vigilance is necessary during treatment initiation, during conversion from one opioid to another, and during dose titration.
Dispose of any unused methadone hydrochloride tablets remaining from a prescription as soon as they are no longer needed. Unused tablets should be flushed down the toilet.
Fertility – Reproductive function hinein human males may be decreased by methadone treatment. Reductions in ejaculate volume and seminal vesicle and prostate secretions have been reported in methadone-treated individuals. Hinein addition, reductions in serum testosterone levels and sperm motility, and abnormalities rein sperm morphology have been reported. Published animal studies provide additional data indicating that methadone treatment of males can alter reproductive function.
Do not take a higher dose of methadone hydrochloride tablets or take it more often than prescribed. This can lead to an overdose and possible death.
Several studies have suggested that infants born to narcotic-addicted women treated with methadone during all or part of pregnancy have been found to have decreased fetal growth with reduced birth weight, length, and/or head circumference compared to controls.
These can Beryllium symptoms that you have taken too much (overdose of) methadone hydrochloride tablets, or the dose is too high for you. They can also Beryllium symptoms of a serious heart reaction. These symptoms can lead to serious problems or death if not treated right away.
The chance is higher if you are or have been addicted Methadontabletten ohne Rezept online to or abused other medicines, street drugs, or alcohol, or if you have a history of mental problems.
General Information About Methadone Hydrochloride Tablets Medicines are sometimes prescribed for purposes other than those listed in patient information leaflet. Do not use methadone hydrochloride tablets for a condition for which it welches not prescribed. Do not give methadone hydrochloride tablets to other people, even if they have the same symptoms you have. Methadone hydrochloride tablets can harm other people and even cause death.
Examples of benzodiazepines include lorazepam, clonazepam, and alprazolam. These drugs should only be used with methadone when other drugs don’t work well enough.
Initial doses should not be determined by previous treatment episodes or dollars spent qua day on illicit drug use.